Many
women, wishing to have a child, do not have ovarian function, or their
ovaries function poorly. Most of them would benefit from using the
eggs of a younger woman. Women who carry a genetic or chromosomal
abnormality may also benefit from donor egg. Almost any woman who has
an intact uterus can carry a pregnancy.
The
egg donor may be a relative or friend of the patient, but most often
the woman who provides the egg is an anonymous donor found through an
agency, or, sometimes through the IVF clinic. The egg donor undergoes
ovarian stimulation for IVF, and the eggs are retrieved just as they
would be if she were trying to get pregnant. The husband of the
patient provides the sperm to fertilize the eggs, or a specimen can be
obtained from a sperm bank.
While
the ovaries of the donor are being stimulated, it is necessary to
prepare the endometrium (uterine lining) of the recipient. It is the
same protocol as for a frozen embryo transfer or gestational carrier
(gestational host). If the woman is still having menstrual periods, it
is necessary to prevent her pituitary gland from stimulating her
ovaries, and therefore, her endometrium. We use Lupron to accomplish
this suppression. We, then administer, first estrogen alone, followed
by estrogen and progesterone to prepare the endometrium for the
embryos. On the day of embryo transfer, a small catheter is placed in
the uterus to deliver the embryos. Estrogen and progesterone
administrations are continued for the first 8 weeks of pregnancy, or
discontinued after 2 weeks if no pregnancy is established.
For
gestational carrier, the process is the same scenario as for the
recipient of donor egg. If a woman is unable, for medical reasons, to
carry a pregnancy, or if she does not have a uterus, her ovaries are
stimulated for IVF. After her eggs are retrieved, they are fertilized
with her husband’s sperm, and her embryos are transferred to the
already prepared uterus of her gestational carrier.
Today,
we have technologies, which permit us to provide pregnancies for
people who were previously unable to have children. There are,
however, circumstances when the stress caused by our technology might
be harmful. For that reason, we believe it is important for the
patient-couple seeking donor egg or gestational carrier to have a
psychological assessment. The introduction of a third party into a
couple’s reproductive relationship could be disturbing. Similarly,
the egg donor or gestational carrier, as well as her spouse should be
evaluated. We wish to avoid upsetting their relationship, and assure
the recipient couple of the stability of the donor or carrier they may
choose to use.
Occasionally,
couples find their own egg donors or gestational carriers. More often,
they rely on an agency to locate the donor or carrier. In our opinion,
the agency should provide the psychological assessments described
above, and anonymity for both the egg donor and recipient. The patient
couple should have all other personal information about the donor. In
the case of gestational carrier, she is known by the patient-couple.
The agency should also provide legal assistance for the patient
couple, which includes contracts, to protect them as well as their
donor or carrier. It is wise for any couple seeking such an agency, to
investigate them. Ask questions. You need to educate yourself about
all the processes, which will involve you.
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